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KarthusMatchups
Master every matchup: stats-driven builds, runes, skills, and laning insights, combined with Master-Tier tips and community contributions.
| Matchup | Threat | Games | WR | Gold @ 15 | Gold Diff | Tips | |
|---|---|---|---|---|---|---|---|
 Diana | Easy | 203 | 45% | +110 | +295 | 💬 No tips yet — Be the first to add a tip! | |
Skill Priority Q Lay Waste Karthus unleashes a delayed blast at a location, dealing damage to nearby enemies. Deals increased damage to isolated enemies.  E Defile Karthus passively steals energy from his victims, gaining Mana on each kill. Alternatively, Karthus can surround himself in the souls of his prey, dealing damage to nearby enemies, but quickly draining his own Mana.  W Wall of Pain Karthus creates a passable screen of leeching energy. Any enemy units that walk through the screen have their Move Speed and Magic Resist reduced for a period. 44.3% WR 185 Matches Summoner Spells  51.6% WR 62 Matches Skill OrderLay Waste Karthus unleashes a delayed blast at a location, dealing damage to nearby enemies. Deals increased damage to isolated enemies. 1 3 5 7 9 Wall of Pain Karthus creates a passable screen of leeching energy. Any enemy units that walk through the screen have their Move Speed and Magic Resist reduced for a period. 4 14 15 17 18 Defile Karthus passively steals energy from his victims, gaining Mana on each kill. Alternatively, Karthus can surround himself in the souls of his prey, dealing damage to nearby enemies, but quickly draining his own Mana. 2 8 10 12 13  Requiem After channeling for 3 seconds, Karthus deals damage to all enemy champions. 6 11 16 Karthus vs Diana Runes                     47.5% WR101 Matches       Starting Items  50.0% WR 38 Matches Core Items   43.8% WR 16 Matches 4th Item Options32.4% WR34 Matches 53.3% WR30 Matches  52.0% WR25 Matches 5th Item Options55.6% WR18 Matches  50.0% WR16 Matches 75.0% WR12 Matches 6th Item Options62.5% WR8 Matches 66.7% WR6 Matches 33.3% WR3 Matches Laning Phase (@15 min)Gold Diff+110 CS Diff+4 XP Diff+111 Ally Ganks1.88 Enemy Ganks2.12 End of GameTotal Gold Diff+295 Total CS Diff+6 Split Push | |||||||
 Khazix | Easy | 187 | 55% | +153 | +796 | 💬 No tips yet — Be the first to add a tip! | |
 JarvanIV | Easy | 178 | 51% | +539 | +1,523 | 💬 No tips yet — Be the first to add a tip! | |
 Ekko | Easy | 165 | 41% | +102 | -341 | 💬 No tips yet — Be the first to add a tip! | |
 Viego | Easy | 157 | 49% | +278 | +641 | 💬 No tips yet — Be the first to add a tip! | |
 Jayce | Easy | 139 | 52% | +14 | -197 | 💬 No tips yet — Be the first to add a tip! | |
 Graves | Easy | 137 | 50% | +153 | -411 | 💬 No tips yet — Be the first to add a tip! | |
 Nami | Easy | 134 | 60% | +12 | -271 | 💬 No tips yet — Be the first to add a tip! | |
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