KarthusMatchups Spreadsheet
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Optimized Karthus builds, runes, skill orders, and matchup strategies — plus expert tips and guides for every Karthus matchup. Brought to you by League of Matchups, your source for counter-picking insights.
| Matchup | Threat | Games | WR | Gold @ 15 | Gold Diff | Tips | |
|---|---|---|---|---|---|---|---|
 Viego  | Easy | 159 | 50% | +308 | +349 | 💬 No tips yet — Be the first to add a tip! | |
Skill Priority Q Lay Waste Karthus unleashes a delayed blast at a location, dealing damage to nearby enemies. Deals increased damage to isolated enemies.  E Defile Karthus passively steals energy from his victims, gaining Mana on each kill. Alternatively, Karthus can surround himself in the souls of his prey, dealing damage to nearby enemies, but quickly draining his own Mana.  W Wall of Pain Karthus creates a passable screen of leeching energy. Any enemy units that walk through the screen have their Move Speed and Magic Resist reduced for a period. 50.38% WR 133 Matches Summoner Spells  64.81% WR 54 Matches Skill OrderQ Lay Waste Karthus unleashes a delayed blast at a location, dealing damage to nearby enemies. Deals increased damage to isolated enemies. 1 3 5 7 9 W Wall of Pain Karthus creates a passable screen of leeching energy. Any enemy units that walk through the screen have their Move Speed and Magic Resist reduced for a period. 4 14 15 E Defile Karthus passively steals energy from his victims, gaining Mana on each kill. Alternatively, Karthus can surround himself in the souls of his prey, dealing damage to nearby enemies, but quickly draining his own Mana. 2 8 10 12 13  R Requiem After channeling for 3 seconds, Karthus deals damage to all enemy champions. 6 11                      50.5% WR105 Matches       Starting Items  29.6% WR 27 Matches Core Items   41.7% WR 12 Matches 4th Item Options 46.2% WR26 Matches 56.3% WR16 Matches 30.8% WR13 Matches 5th Item Options54.5% WR11 Matches  40.0% WR10 Matches 50.0% WR8 Matches 6th Item Options83.3% WR6 Matches  66.7% WR3 Matches 33.3% WR3 Matches Laning Phase (@15 min)Gold Diff+308 CS Diff+13 XP Diff+565 Ally Ganks2.03 Enemy Ganks1.96 KDA3 / 2 / 3 End of GameTotal Gold Diff+349 Total CS Diff+26 Total XP Diff0 KDA8 / 6 / 9 Split Push | |||||||
 JarvanIV | Easy | 131 | 56% | +672 | +1917 | 💬 No tips yet — Be the first to add a tip! | |
 LeeSin | Easy | 99 | 44% | +481 | +1420 | 💬 No tips yet — Be the first to add a tip! | |
 Kayn | Easy | 95 | 47% | +215 | +335 | 💬 No tips yet — Be the first to add a tip! | |
 Khazix | Easy | 84 | 56% | +301 | +637 | 💬 No tips yet — Be the first to add a tip! | |
 Ekko | Easy | 83 | 45% | +245 | +446 | 💬 No tips yet — Be the first to add a tip! | |
 Thresh  | Easy | 83 | 53% | +5 | -319 | 💬 No tips yet — Be the first to add a tip! | |
 Lulu | Easy | 82 | 46% | +108 | -550 | 💬 No tips yet — Be the first to add a tip! | |